Vaping is the act of inhaling a heated, aerosolized substance. It is critical to distinguish vaping from smoking. Smoking is the inhalation of a burned substance. The main difference between the two E Cigarettes: The Truth Behind 'Safer than Cigarettes' and Exploring Their Mechanisms TiNHiH Foundation How Do E Cigarettes Work? Did you know E cigarettes are targeting youth and becoming trending, recent study found E cigs may encourage conventional cigarette use in youth. Mind Matters: How do Vaping Devices Work?